Monthly Archives: April 2024

Resting-state fMRI has become a popular tool to study how distant brain areas are functionally connected

Utilizing data from the IMAGEN study that included longitudinal fMRI and measures of PS at follow-up, Papanstasiou et al. observed increases in right frontal activation during reward anticipation and feedback of win from age 14 to 19 that was associated … Continue reading

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Antiretroviral therapy has dramatically improved the survival and quality of life of people with HIV

Rates have remained at least 2.5 times higher among males since 2016 . This is among the first national investigations to examine reasons for fentanyl exposure in a nuanced manner. With respect to route of administration, dermal use decreased, and … Continue reading

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Two CTN trials have employed EMA and passive sensing technologies

This pattern highlighting the effectiveness of TES was evident across diverse groups of patients, including those with stimulant, cannabis and alcohol use disorders , those with and without criminal justice involvement those with and without Internet access , and across both … Continue reading

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This typical pattern of neural maturation occurred among adolescents who remained nondrinkers

We found significant drinking status × time interactions in a number of distinct and reproducible brain regions commonly associated with response inhibition. Prior to initiating substance use, adolescents who initiated heavy use showed less BOLD activation during inhibitory trials in frontal … Continue reading

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Eligible participants were invited to the laboratory for additional screening

Alcohol dependent patients who underwent cue-exposure extinction training had larger decreases in neural alcohol cue-reactivity in mesocorticolimbic reward circuitry than patients who had standard clinic treatment. Cognitive bias modification training, which similarly trains individuals to reduce attentional bias towards alcohol … Continue reading

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Examining recognition and delayed recall was a critical first step to inform future diagnostic improvements

Marsland et al., 2015 did find that IL-6 and CRP were associated with worse memory and smaller hippocampal volumes in middle-aged adults; however, it was cortical grey matter volume, not the hippocampus, that mediated the relationship between inflammation and memory. … Continue reading

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Volumetric subcortical regions of interest included the hippocampus as well as the basal ganglia

The majority of older PWH are currently between the ages of 50 to 65, with a much smaller percentage over the age of 65. However, aging trends in the HIV population are predicted to continue . Additionally, age-associated physical comorbidities appear … Continue reading

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Previous studies have focused primarily on alcohol users but have not excluded participants for nicotine use

This suggests that brain areas implicated in processes such as reward and cognition show the most consistent gray matter atrophy in alcohol dependent individuals, but it is unclear whether overall amount of alcohol consumption or aspects of dependence severity explain … Continue reading

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The peer group of patients in SUD treatment may still be using drugs and engaging in risk behaviors

Separate multinomial logistic regression models were performed for each sexual risk behavior: unprotected sexual intercourse with regular partners, unprotected sexual intercourse with casual partners, number of sex partners, having at least one high risk sex partner, and engaging in sex … Continue reading

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Any letter-writer signatures and titles were deleted prior to analysis to avoid introducing bias

Our longer-term goals will be to see the effects of this system on the promotion process within the department with an expectation that more junior faculty will become eligible for advancement. These effects will be evaluated by tracking the progress … Continue reading

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