The regression models incorporated all individual- and state level controls and annual fixed effects

Our survey respondents, because of their large holdings, may be unusually exposed to cannabis growers physically because their larger properties may have more contact with cannabis growers. At the same time, these respondents might be better able to survive economically in a Humboldt County without cannabis. It is unclear if the experiences and perspectives of many Humboldt County smaller landowners would be similar to those of these large landowners. For many in Humboldt County, the impacts of cannabis production on property and the environment are a central concern. Respondents mentioned problems involving shared roads and fences, illegal garbage dumping and contamination, deforestation, fire hazards, feral dogs and impacts on wildlife and domestic livestock. One respondent wrote that “Growers leave a mess, steal water, tear up roads, let guard dogs damage neighbors’ property, including livestock, poison wildlife, increase soil erosion and threaten people.” In many ways, it seems that land ethics are at the center of the concerns that traditional agricultural producers harbor about the new wave of cannabis growers. Though respondents remarked on cannabis growing’s direct impacts on the environment, they also largely agreed that the cannabis industry is causing fewer young people to enter traditional farming careers — and that growers are taking over working lands. It is unknown if the rates at which successive generations stay in the family business are lower in Humboldt County than in rural communities less influenced by cannabis. For families who have managed and lived off these lands for decades — most of them for more than 50 years — these shifting stewardship ethics threaten their immediate environment as well as their very identity.

One of the more controversial questions in drug policy today is whether the trend toward legalizing marijuana for medicinal and adult recreational use could increase illicit marijuana use among young people . Since 1996, 28 U.S. states and the District of Columbia have legalized the production and sale of marijuana for medicinal use , clone rack and eight have legalized marijuana for adult recreational use. Medical marijuana laws could potentially increase the availability of marijuana and reduce perceptions of its harmfulness, leading more young people to try it. State medical marijuana laws include regulations that protect young people from illegally obtaining marijuana . But if these restrictions are not carefully enforced, young people could gain increased access to marijuana through the diversion of medical marijuana into illegal markets, which could also lower its price . Marijuana use by young people is associated with lasting detrimental changes in cognitive functioning of the developing brain, and poor educational and occupational outcomes . Use increases the risk of unintentional injuries and auto fatalities, mood and psychotic disorders, and drug dependence, especially when use is initiated at a young age . Long term marijuana smokers have a disproportionate burden of upper respiratory illnesses, including chronic bronchitis and some cancers, and an increased risk of cardiovascular disease . Medical marijuana producers and retailers are promoting new, more potent products such as oils often used as inhalants with tetrahydrocannabinol concentrations ranging from 40 to 70 percent . They are also developing new products that appeal to youth, such as packaged edibles and candies, that may increase the hazard of overdose due to their relatively slow rates of absorption and perceived intoxication .

These products could increase the risk of overdose in young people, who tend to be less experienced users with low tolerance levels. Studies have reported little evidence that medical marijuana laws increase marijuana use among young people , although well controlled studies consistently report increased consumption in adults . Using the Youth Risk Behavior Survey, researchers have compared high school students’ consumption before and after medical marijuana laws were enacted, finding no evidence of rising consumption on a national basis . A national study of 12–17 year old found that medical marijuana laws had no causal impact on consumption , as did a carefully controlled national study of 13–18 year olds . Wen et al. reported a five percent increase in the likelihood of trying marijuana among 12–20 year olds who dwell in states with medical marijuana laws, but the study was limited by the need to pool such a broad range of ages. Prior studies have ignored or been unable to detect age related variation in the impact of medical marijuana laws by pooling children aged 12–17, or even 12–24, or by studying particular age groups in isolation. Age-related variation is important to capture because young peoples’ access to marijuana and their developmental susceptibility to drug related harms differs by age . Most studies have focused on high school students who are likely to have greater access to marijuana and are more susceptible to social pressures than early adolescents . Meanwhile, young adults different substantially from these younger groups, both in terms of development and access to drugs, being in the peak years of engagement with psychoactive substances during the lifespan .

We performed multi-level, serial cross-sectional analyses on 10 annual waves of the U.S. National Survey on Drug Use and Health , from 2004 to 2013. Unlike many prior studies, ours included the key years of 2010–2013—a period of rapid acceleration in the number of states implementing medical marijuana laws , but before state recreational marijuana laws began implementation. In addition, our analyses compared young people across developmentally distinct age groups to account for important age-related heterogeneity in access to marijuana, in the propensity to experiment with psychoactive substances, and in the potential harms of marijuana use.We examined three dichotomous outcomes at the individual level: self-reports of the accessibility of marijuana, consumption of marijuana within the past month, and initiation or first-time use of marijuana during the past year. The NSDUH framing of the marijuana questions references smoking, edibles, and oils. Individual-level, age-appropriate predictors from the NSDUH dataset were included in the analysis. Across all three age groups, these included sex, race/ethnicity, family income, poor or fair health, and living in an urban area. We included an indicator of poor or fair health status to control for the possibility that participants in medical marijuana states might engage in the legal use of marijuana for health reasons. For early and late adolescents, we also controlled for parental monitoring and participation in group fights, variables that could be indicators of the protective factor of parental involvement and the risk factor of delinquent behavior, respectively. For young adults, additional controls included employment, college attendance, parental status, and marital status. These are strong protective factors mitigating against drug use in this age group . We augmented the NSDUH data with annually updated state-level data on medical marijuana laws and other relevant control variables. For state-level controls, we drew on publicly available sources such as Polidata , including per capita drug courts and whether or not marijuana possession had been decriminalized. We considered a wider range of state-level controls representing demographic, political and religious factors, and aspects of state drug control policies. For the sake of parsimony, we included controls that were most associated with outcome variables. Data collection on state medical marijuana laws included gathering all state statutes and subsequent regulations, 4×8 tray grow and validating information against publicly available data sources and through telephone calls with state officials. Throughout the study, we conducted regular updates to monitor changes in regulations and amendments to state laws . Analyses incorporated a dichotomous measure reflecting whether a state did or did not have a medical marijuana law enacted during any given year of observation. Thus, a law passed or enacted at any point in a calendar year would count that state as a medical marijuana state for that year’s analysis. We also examined a wide range of characteristics of state laws, such as the amounts of marijuana legally allowed for possession and home cultivation, medical conditions covered, and the number of dispensaries in each state. Through a systematic measurement process, we created and validated a scale capturing the capacity of a given medical marijuana law to control marijuana distribution and diversion into illegal markets .We concatenated 10 annual waves of the NSDUH and all state-level indicators into a single data file. We conducted all analyses using Stata version 13 . For descriptive analyses of each survey year, we used weights to adjust for sampling design effects and non-response ; similar weights were not available for multi-year analyses. Following Williams and others , we accounted for shared variance among participants within states by calculating standard errors clustered at the state level in our regression models.

Our analytic approach used logistic regression to predict marijuana consumption and initiation at the individual level separately for early adolescents, late adolescents, and young adults. A key analytic concern is that people in states that pass medical marijuana laws hold more permissive views about the drug . These more positive perceptions about marijuana may drive both the passage of the medical marijuana laws and higher rates of consumption . We incorporated that possibility into our uncontrolled comparisons of young people who dwell in states with medical marijuana laws compared to those who do not . By controlling for state-level fixed effects , we were able to examine whether medical marijuana laws have distinct causal impacts on marijuana consumption and initiation . The coefficients for each state controlled for any state-specific confounding not already captured by other control variables in the models. This technique allowed us to rule out the possibility that unobserved state-level confounders account for any associations found between state medical marijuana laws and young people’s consumption and initiation of use.Using the most recent NSDUH survey, 2013, we compared rates of access to marijuana, past-month marijuana use and past-year initiation across early and late adolescent youth and young adults. Table 1 shows pronounced differences in the populations of young people living in states with medical marijuana laws compared with those who were not. These demographic differences—especially ones associated with drug-related attitudes—underscore the importance of applying individual-level controls in the analysis. For example, in 2013, individuals living in medical marijuana states were disproportionately white and Hispanic. Young adults living in medical marijuana states were comparatively less likely to be married and to have children. Figure 1 shows a positive age gradient in rates of reporting that marijuana is easily accessible and in past-month marijuana use: The highest prevalence occurred among young adults at 19.1%, then 11.9% of late adolescents and 2.2% of early adolescents . In contrast, initiation of marijuana use in the past year was most common among late adolescents , with young adults the next most likely to initiate marijuana use and early adolescents the least likely to have tried marijuana for the first time in the past year .Table 2 shows logistic regression models predicting past month marijuana consumption that include all individual and state-level controls, and annual and state-level fixed effects. Results provided no evidence of a causal relationship between living in a state where medical marijuana was legal and the past month use of marijuana. Across all age groups, the odds ratio associated with medical marijuana state residence was not statistically significant. Table 3 provides similar fully controlled results for logistic regression analyses predicting past-year initiation of marijuana use. Results show that young adults dwelling in states that have legalized medical marijuana are significantly more likely to initiate marijuana use than counterparts in non-medical marijuana states . Such a relationship is not evident for early or late adolescents . We performed additional analyses to rule out several alternate explanations of these findings. Incorporating the amount of time since the passage of the medical marijuana law into our models produced similar results regardless of duration of the law. To rule out the possibility that young adults are more likely to initiate marijuana use due to mental health conditions, which in some states are legally allowed indications for a medical marijuana prescription, we estimated an alternate version of the models that included additional mental health-related variables, specifically, past-year use of mental health treatment and past-year unmet need for mental health treatment. After introduction of these additional controls, the effect of living in medical marijuana state remained statistically significant for young adults . We also considered the possibility that states with less restrictive medical marijuana laws could have more significant impacts on young people.

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