Author Archives: hemp2022

It is a clinically defined nosological entity with multi-factorial but poorly understood etiologic mechanisms

CBSST appears to be an effective intervention to address these concerns that requires minimal resources and a relatively brief treatment interval, making it ideally suited to adaptation to a variety of clinical settings. Future studies will compare CBSST to standard … Continue reading

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The results of our analysis underscore the importance of frequent STI screening among PWH

Approximately 23% reported using alcohol and drugs prior to sex in the last six months. Participants who had a partner on PrEP reported a higher number of sex partners in the last six months compared to those with only HIV-positive partners and those … Continue reading

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Resting-state fMRI has become a popular tool to study how distant brain areas are functionally connected

Utilizing data from the IMAGEN study that included longitudinal fMRI and measures of PS at follow-up, Papanstasiou et al. observed increases in right frontal activation during reward anticipation and feedback of win from age 14 to 19 that was associated … Continue reading

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Antiretroviral therapy has dramatically improved the survival and quality of life of people with HIV

Rates have remained at least 2.5 times higher among males since 2016 . This is among the first national investigations to examine reasons for fentanyl exposure in a nuanced manner. With respect to route of administration, dermal use decreased, and … Continue reading

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Two CTN trials have employed EMA and passive sensing technologies

This pattern highlighting the effectiveness of TES was evident across diverse groups of patients, including those with stimulant, cannabis and alcohol use disorders , those with and without criminal justice involvement those with and without Internet access , and across both … Continue reading

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This typical pattern of neural maturation occurred among adolescents who remained nondrinkers

We found significant drinking status × time interactions in a number of distinct and reproducible brain regions commonly associated with response inhibition. Prior to initiating substance use, adolescents who initiated heavy use showed less BOLD activation during inhibitory trials in frontal … Continue reading

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Eligible participants were invited to the laboratory for additional screening

Alcohol dependent patients who underwent cue-exposure extinction training had larger decreases in neural alcohol cue-reactivity in mesocorticolimbic reward circuitry than patients who had standard clinic treatment. Cognitive bias modification training, which similarly trains individuals to reduce attentional bias towards alcohol … Continue reading

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Examining recognition and delayed recall was a critical first step to inform future diagnostic improvements

Marsland et al., 2015 did find that IL-6 and CRP were associated with worse memory and smaller hippocampal volumes in middle-aged adults; however, it was cortical grey matter volume, not the hippocampus, that mediated the relationship between inflammation and memory. … Continue reading

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Volumetric subcortical regions of interest included the hippocampus as well as the basal ganglia

The majority of older PWH are currently between the ages of 50 to 65, with a much smaller percentage over the age of 65. However, aging trends in the HIV population are predicted to continue . Additionally, age-associated physical comorbidities appear … Continue reading

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Previous studies have focused primarily on alcohol users but have not excluded participants for nicotine use

This suggests that brain areas implicated in processes such as reward and cognition show the most consistent gray matter atrophy in alcohol dependent individuals, but it is unclear whether overall amount of alcohol consumption or aspects of dependence severity explain … Continue reading

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