Author Archives: hemp2022

Our findings indicate there is a lack of community‐based pathways into substance use care

It is possible that participants in our study were obtaining care in safety‐net primary care settings with CCMs. Alternatively, the reduced odds of unmet need amongst those who had regular care providers could reflect other factors that we did not … Continue reading

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Age of onset was determined for all comorbid disorders based on the SSAGA-IV

DSM-IV diagnoses for all disorders were made algorithmically from SSAGA information. However for these analyses we also generated a DSM-5 diagnosis for AUD in the following way. Individual alcohol symptoms were queried, starting with symptoms of DSM-IV alcohol dependence and alcohol … Continue reading

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Some of the cells record zero deaths from one or more of the causes we study

Since 2014, overall life expectancy in the US has fallen for three years in a row, reversing a century-long trend of steadily declining mortality rates. This decrease in life expectancy reflects a dramatic increase in deaths from so-called “deaths of … Continue reading

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Frontal theta response underlies a variety of cognitive processes including reward processing

We uniquely examined how GM status is related to risk for SUDs. This is an important contribution as studies assessing SUDs by gender identity are limited and typically focused on substance use instead of abuse . In contrast to findings … Continue reading

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Estimating the content of anandamide in the CNS may be useful to delineate its possible roles in neural signaling

Like other phospholipid metabolites, N-acyl PEs and NAEs accumulate rapidly in the CNS after the inception of an ischemic injury . This response, likely caused by postischemic rises in the concentration of free Ca21 , may confuse quantitative analysis unless … Continue reading

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The magnitude of this association did not change appreciably after adjusting for potential confounders

Caretakers provided informed consent and adolescents provided assent until age 17 and consent thereafter. We restricted analysis to adolescents at ages, as substance use by year was rare at younger ages: 93.9% and 84.5% did not use marijuana or alcohol, … Continue reading

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SUD treatment initiation and retention are key clinical goals for SUD patients

Notably, the correlations between cigarette demand indices and WSWS negative affect scores have not been previously reported. Although our participants were relatively satiated with smoking when they completed the CPT, these findings suggest that smokers’ withdrawal experience was positively associated with … Continue reading

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The risk pathway from anhedonia to marijuana use may be incremental to risk of other drug use

The participation of some participants can be interrupted due to drug-related police arrest or methadone treatment fatigue. This limitation can be minimized as we will select clinics with low drop-out rates. We have officially informed the local police on the … Continue reading

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The COVID-19 pandemic has disrupted health and social services worldwide

Raw scores for each of these component tests were converted to demographically-adjusted T-scores , including adjustments for age, education, gender, and ethnicity as available for each test. The demographically adjusted T-scores for each test were then converted into deficit scores, which reflect degree … Continue reading

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The relationship between inflammation and depressive mood remained after accounting for ethnicity

If the link between inflammation and depression is causal, our results suggest that treatment with selected anti-inflammatory medications might benefit mood and life quality in some PWH. Depressed mood was specifically associated with a factor loading on d-dimer, IL-6 and CRP. Factor analysis is … Continue reading

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