Author Archives: hemp2022

There are substantial uncertainties in the risk assessment of odorants, the greatest being how likely it is that the individual odorants monitored actually are the main contributors to the overall odor sensed. Missing the key odorants invalidates the study. OPM … Continue reading →

The scale is 0 to 5 , and extrapolations to 0 are used to predict the ODTC50. This approach has led to good agreement with ODTC50 values from the literature. Another odor-intensity measurement system is used more widely than OPM. ASTM … Continue reading →

Even much slower trains of action potentials result in a buildup of Ca2 in pyramidal cell dendrites. This Ca2 level perfectly correlates with spike frequency ; therefore, it may induce endocannabinoid release in an activity-dependent manner, if coupled to a coincident activation of … Continue reading →

Such an “inverted U” dose-response relationship warrants further investigation but may be explained by the activation of different cannabinoid receptor types, likely possessing distinct agonist sensitivity , or by the dose-dependent engagement of excitatory or inhibitory afferent pathways of the … Continue reading →

The fact that the cannabinoid antagonist SR141716A prevents these effects suggests that AM404 may act by preventing anandamide inactivation and enhancing its interactions with cannabinoid receptors. Importantly, however, AM404 also can be transported inside cells , where it may reach … Continue reading →

But most clients do not quit using; on the contrary, many significantly increase their daily dose, so the intervention reduces their disorder on some criteria while possibly increasing their disorder by other criteria. Figure 1F, reproduced from Cramer et al. … Continue reading →

Importantly, we examined the association of alcohol use and ART adherence in the context of other important variables such as use of other substances , major depressive disorder , global cognitive function. We hypothesized that PLWHA who are at-risk drinkers … Continue reading →

The physical environment also plays a role. Varying wind direction and speed lead to the transitory nature of odors, and multiple sources in the vicinity lead to difficulty in source attribution. Even temperature and humidity play roles in the perception … Continue reading →

Subjects were defined as having DM if they answer ‘yes’ to the question ‘Have you ever been told you have sugar/diabetes?’ or had a fasting blood glucose level $126 mg/dl . Of the 719 patients with DM, 418 answered the question … Continue reading →

In the US, the refusal to enfranchise Blacks or Native Americans led to the development of racial categories, and these categories were in the US census from the beginning. In some of the federated states of the US, there were … Continue reading →