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Anandamide synthesis can be elicited in vitro by a variety of agents that elevate intracellular Ca2+ levels
Although separate enzymes cata lyze the syntheses of anandamide and NAPE, the two events are likely to occur simultaneously because Ca2+- stimulated anandamide production is often accompanied by de novo formationof NAPE .For example, the Ca2+ ionophore ionomycin stimulates [ 3 … Continue reading
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