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All participants had cognitive symptoms of sufficient severity to warrant a HAND diagnosis

Despite the success of antiretroviral therapy, approximately 20–50% of HIV-infected individuals have HIVassociated neurocognitive disorder. HIV infection and stimulation of monocytes and lymphocytes promotes trafficking into the central nervous system, triggering a neuroinflammatory response. Within the CNS, inflammation leads to … Continue reading

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We categorized responses as TBI if any head injury resulted in loss of consciousness

Participants provided written informed consent for participation.We assessed the prevalence, severity, and duration of pain using questions from the Brief Pain Inventory .We asked participants whether they had experienced pain or taken medicine for pain in the past week. Next, … Continue reading

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Reasons for coming off study treatment were balanced between treatment arms

Craving likely represents a more proximal determinant of alcohol use than stimulation and sedation, which are shown to indirectly influence alcohol self-administration through craving . An additional exploratory aim was to test whether a characteristic of AUD severity, withdrawal-related dysphoria, … Continue reading

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Research investigating this theory has been limited and results have been inconsistent

More importantly, greater reductions in discounting predict a greater likelihood of protracted abstinence among cocaine users and smokers . Thus, if a causative link between D2 /D3 receptor availability and temporal discounting is established, it may lead to the development of … Continue reading

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Less is understood about the long-term effects of vaping on asthma

E-cigarettes have been marketed as a form of harm reduction from traditional cigarette smoking, but neither the safety nor the efficacy of these devices has been established, and little is known about the short and long term pulmonary and systemic … Continue reading

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The present study showed an increase in the use of home prepared foods after a cancer diagnosis

For home prepared diets, a list of ingredients and the source of the recipe was requested. Participants also identified where they obtained information on choosing the diet. For the supplement section, participants answered questions on which products were added or stopped … Continue reading

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No main effects of PRS or neural connectivity on COVID-19 drinking outcomes were observed

Among methodologic considerations and limitations, the main outcome measure in this study, initiation of any tobacco use, is a critical milestone, particularly among youth for whom daily smoking may develop over several years.However, long-term established tobacco use deserves attention in … Continue reading

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β-diversity measures between groups were compared via the Wilcoxon-Mann-Whitney test

The oral microbiome is one of the most diverse microbial niches in the human body, including over 600 different microorganisms . It is in continual contact with the environment, and has been shown to be susceptible to many environmental effects. … Continue reading

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Weekly supervision includes reviewing audio recordings of BI sessions and portal transcripts

We will also examine intervention efficacy on other opioid outcomes , other substance misuse and consequences, and impaired driving. Further, we will also measure intervention costs and identify moderators/mediators of efficacy. In this paper, we describe the RCT protocol with … Continue reading

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It is a clinically defined nosological entity with multi-factorial but poorly understood etiologic mechanisms

CBSST appears to be an effective intervention to address these concerns that requires minimal resources and a relatively brief treatment interval, making it ideally suited to adaptation to a variety of clinical settings. Future studies will compare CBSST to standard … Continue reading

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